EGAD: protein design and mutant stability and affinity prediction
Description
EGAD is a free, open-source software package for protein design and prediction of mutation effects on protein folding stabilities and binding affinities to 1kcal/mol. EGAD can also consider multiple structures simultaneously for designing specific binding proteins or locking proteins into specific conformational states. In addition to natural protein residues, EGAD can also consider free-moving ligands with or without rotatable bonds.
Documentation, Other Resources
Citation
Last modified: 12/31/06
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