Structural > Crystallization
Bioinformatics tools
Bioinformatics tools from the Israel Structural Proteomics Center. |
CLIMS
CLIMS (Laboratory Information Management System) for protein Crystallography that features a novel graphical interface to a relational database, and assists all aspects of protein crystallisation, including: 1) protein expression and handling; 2) crystallisation optimisation; and 3) visualisation of results and preliminary diffraction data. |
Crystal Growth 101 literature from Hampton Research
Are you looking to get started in crystallization? Check out some of Hampton Reseearch's Crystal Growth 101 guides to help you. |
Crystallization Tips
A collection of crystallization tips from Hampton Research. |
DisEMBL
DisEMBL is a computational tool for prediction of disordered/unstructured regions within a protein sequence. As no clear definition of disorder exists, we have developed parameters based on several alternative definitions, and introduced a new one based on the concept of ``hot loops'', i.e. coils with high temperature factors. |
EGAD: protein design and mutant stability and affinity prediction
EGAD is a free, open-source software package for protein design and prediction of mutation effects on protein folding stabilities and binding affinities to 1kcal/mol. EGAD can also consider multiple structures simultaneously for designing specific binding proteins or locking proteins into specific conformational states. In addition to natural protein residues, EGAD can also consider free-moving ligands with or without rotatable bonds. |
FoldIndex
FoldIndex tries to answer to the question: Will this protein fold? It's a dynamic and interactive process that estimates the local and general probability for the provided sequence, under specified conditions, to fold. |
GLOBPLOT 2
Intrinsic Protein Disorder, Domain & Globularity Prediction. |
HWI High Throughput Crystallization Service
The high-throughput crystallization laboratory at HWI will prepare crystal-growth screening experiments in 1536-well microassay plates free to anyone who will permit the results of the experiment to be added to the HWI crystallization database. This service is otherwise provided for a fee of $1,000 per plate. We will not publicly disclose information on any sample we receive for crystallization trials without the expressed written consent of the investigator(s). |
PONDR
Disordered regions (DRs) are entire proteins or regions of proteins which lack a fixed tertiary structure, essentially being partially or fully unfolded. |
POODLE
POODLE (Prediction Of Order and Disorder by machine LEarning) is a system that predicts disorder regions using amino acid sequence alone. The POODLE system consists of three predictions, short disorder regions prediction, long disorder regions prediction and unfolded protein prediction. |
RONN
Regional Order Neural Network (RONN) to predict protein disorder. |
RaCC
RaCC (Rare Codon Calculator) determines the number of rare E. coli codon in a given DNA sequence. |
The Protein Crystallization Home Page of Terese Bergfors
The Protein Crystallization Page includes a pictorial library of crystallization drop phenomena. |
VAZyMolO
VaZyMolO is a database dealing with viral sequences at the protein level. Its aim is to define modules suitable for high expression, solubility, and crystallization. |